What is Kisspetin-10
Kisspetin-10 appears as a white lyophilized powder. It is a bioactive peptide composed of 10 amino acids and is a short-chain subtype of the Kisspeptin family. It is a high-affinity agonist of the KISS1R (GPR54) receptor, and exerts its effects by activating this receptor.
Main Effects
1. Regulation of reproductive endocrinology: Research indicates that Kisspeptin-10 effectively stimulates the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby playing a pivotal role in regulating the onset of puberty and the function of the reproductive axis. Consequently, it is frequently utilized in animal models to study reproductive development and the mechanisms underlying infertility.
2. Inhibition of tumor metastasis: Recent *in vitro* studies demonstrate that treatment with Kp-10 reduces cell viability and migratory capacity in triple-negative breast cancer cells and induces the expression of apoptosis-related genes, highlighting its potential as an anti-tumor agent.
How to Use
Reconstitute with bacteriostatic water;
Subcutaneous injection is commonly used in animal experiments;
Typical dosage range for animal experiments: 0.1–1 mg; determine the dosing frequency based on the experimental model.
